Andrew MacPherson’s LABScon 25 talk examines large-scale cryptocurrency crime affecting decentralized finance, including attacks against browser-based wallet interactions, smart contracts, and crypto applications. The excerpt highlights major attack patterns such as the $1.5 billion Bybit heist, supply chain compromises, and “drainers as a service.” It also describes laundering through cross-chain swaps, mixers, and non-KYC platforms, showing how attackers move stolen funds despite blockchain transparency. The material matters for crypto-threat monitoring because it explains tactics and laundering behavior that analysts may encounter when tracking theft from DeFi and wallet ecosystems.